Zonisamide: aspects in neuroprotection

Thomas W Rösler; Oscar Arias-Carrión; Günter U Höglinger

doi:10.1016/j.expneurol.2010.04.017

Zonisamide: aspects in neuroprotection

Exp Neurol. 2010 Aug;224(2):336-9. doi: 10.1016/j.expneurol.2010.04.017. Epub 2010 May 4.

Authors

Thomas W Rösler¹, Oscar Arias-Carrión, Günter U Höglinger

Affiliation

¹ Department of Neurology, Philipps-University, Marburg, Germany.

PMID: 20450911
DOI: 10.1016/j.expneurol.2010.04.017

Abstract

Zonisamide is widely used as an antiepileptic drug. Two studies published recently in Experimental Neurology focus on the drug's neuroprotective effect. In the present commentary, we discuss the significance of their findings and aspects of zonisamide in neuroprotection.

Publication types

Comment

MeSH terms

Animals
Anticonvulsants / pharmacology*
Anticonvulsants / therapeutic use
Antiparkinson Agents / pharmacology
Antiparkinson Agents / therapeutic use
Humans
Isoxazoles / pharmacology*
Isoxazoles / therapeutic use
Neurons / drug effects
Neurons / pathology
Neuroprotective Agents / pharmacology*
Neuroprotective Agents / therapeutic use
Parkinson Disease / drug therapy
Parkinson Disease / pathology
Zonisamide

Substances

Anticonvulsants
Antiparkinson Agents
Isoxazoles
Neuroprotective Agents
Zonisamide