No long-term weight maintenance effects of gelatin in a supra-sustained protein diet

Physiol Behav. 2010 Sep 1;101(2):237-44. doi: 10.1016/j.physbeh.2010.05.005. Epub 2010 May 10.

Abstract

In the short-term, gelatin showed stronger hunger suppression and less energy intake compared with other proteins. This study investigated if a supra-sustained gelatin-milk protein (GMP) diet improves weight maintenance (WM) compared with a sustained milk protein (SMP) diet and supra-sustained milk protein (SSMP) diet during a 4-months WM period after 8-week weight loss (WL) in sixty-five healthy subjects (28.6+/-3.4kg/m(2); 44+/-10years). Absolute protein intake was kept constant (sustained) throughout per subject. Diets were: protein(P)/fat(F)/carbohydrate(C): 15/40/45% of energy (En%) (SMP) and 30/25/45 En% (SSMP or GMP) for weeks 9-16. Diets on weeks 17-24: P/F/C: 30/35/35 En% (SMP) and 60/5/35 En% (SSMP or GMP). From weeks 8 to 16, and weeks 16 to 24, changes in BMI were similar between the GMP (-0.4+/-0.6 and 0.3+/-0.7kg/m(2) respectively), and the SMP (-0.7+/-0.9 and 0.1+/-0.7kg/m(2) respectively) and SSMP (-0.6+/-0.6 and 0.3+/-0.6kg/m(2) respectively) diets. Sparing of fat free mass (FFM): increases/decreases in FFM%/fat-mass% from weeks 8 to 16 were similar between the GMP and both control diets, and maintained from weeks 16 to 24. In conclusion, all 3 diets resulted in a successful WM period, while a GMP diet does not improve body weight maintenance and related variables after weight loss compared with a SMP and SSMP diet.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Blood Chemical Analysis / methods
  • Blood Pressure / drug effects
  • Body Composition / drug effects
  • Dietary Proteins / administration & dosage
  • Dietary Proteins / pharmacology*
  • Drug Delivery Systems
  • Energy Intake / drug effects
  • Female
  • Gelatin / administration & dosage
  • Gelatin / pharmacology*
  • Heart Rate / drug effects
  • Humans
  • Male
  • Middle Aged
  • Milk Proteins / administration & dosage
  • Milk Proteins / pharmacology*
  • Motor Activity / drug effects
  • Obesity / diet therapy*
  • Obesity / physiopathology
  • Single-Blind Method
  • Time Factors
  • Waist Circumference / drug effects
  • Weight Loss / drug effects*
  • Young Adult

Substances

  • Dietary Proteins
  • Milk Proteins
  • Gelatin