Skin biomedical optical imaging system using dual-wavelength polarimetric control with liquid crystals

J Biomed Opt. 2010 Mar-Apr;15(2):026024. doi: 10.1117/1.3394338.


Spectropolarimetric skin imaging is becoming an attractive technique for early detection of skin cancer. Using two liquid crystal retarders in combination with a dual-band passive spectral filter and two linear polarizers, we demonstrate the spectral and polarimetric imaging of skin tissue in the near infrared. Based on this concept, a compact prototype module has been built and is being used for clinical evaluation.

MeSH terms

  • Dermoscopy / instrumentation*
  • Equipment Design
  • Equipment Failure Analysis
  • Humans
  • Liquid Crystals*
  • Pilot Projects
  • Refractometry / instrumentation*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Skin Neoplasms / pathology*