Motor proteins: kinesin drives with an underhead cam

Matthew J Lang; Wonmuk Hwang

doi:10.1016/j.cub.2010.03.015

Motor proteins: kinesin drives with an underhead cam

Curr Biol. 2010 May 11;20(9):R408-10. doi: 10.1016/j.cub.2010.03.015.

Authors

Matthew J Lang¹, Wonmuk Hwang

Affiliation

¹ Department of Biological Engineering, MIT, Cambridge, MA 02139, USA. mjlang@mit.edu

PMID: 20462483
DOI: 10.1016/j.cub.2010.03.015

Abstract

A high-resolution cryo-EM structure of kinesin bound to its microtubule track allows for near-atomistic visualization of nucleotide-dependent conformational changes in this motor protein.

MeSH terms

Adenosine Triphosphate / physiology
Animals
Energy Metabolism / physiology
Kinesins / physiology
Kinesins / ultrastructure*
Microtubules / physiology
Microtubules / ultrastructure
Motion

Substances

Adenosine Triphosphate
Kinesins