Development of trifunctional probes for glycoproteomic analysis

Chem Commun (Camb). 2010 Aug 14;46(30):5575-7. doi: 10.1039/c0cc00345j. Epub 2010 May 13.

Abstract

A new trifunctional probe, assembled using a cleavable linker, is useful for efficient enrichment and detection of alkynyl sugar-tagged biomolecules.

MeSH terms

  • Cell Line, Tumor
  • Glycoproteins / analysis*
  • Humans
  • Male
  • Molecular Probes / chemical synthesis
  • Molecular Probes / chemistry*
  • Molecular Structure
  • Prostatic Neoplasms / chemistry
  • Proteomics / methods*

Substances

  • Glycoproteins
  • Molecular Probes