Primary immunodeficiencies of dogs and cats

Vet Clin North Am Small Anim Pract. 2010 May;40(3):425-38. doi: 10.1016/j.cvsm.2010.01.001.


Primary immunodeficiencies are congenital defects that affect formation or function of the immune system. Congenital immunodeficiency should be considered as a differential diagnosis for repeated infections in a young animal. Defects in the immune system may lead to complete or partial loss of immunity. Some animals with mild immunodeficiency can be managed with long-term antibiotic therapy.

Publication types

  • Review

MeSH terms

  • Animals
  • Autoimmune Diseases / immunology
  • Autoimmune Diseases / veterinary*
  • Cat Diseases / immunology*
  • Cats
  • Cytotoxicity, Immunologic
  • Dog Diseases / immunology*
  • Dogs
  • Immune Complex Diseases / immunology
  • Immune Complex Diseases / veterinary*
  • Immune Tolerance
  • Immunity, Innate
  • Immunologic Deficiency Syndromes / immunology
  • Immunologic Deficiency Syndromes / veterinary*