There are many autoimmune diseases recognized in humans; many of these have counterparts in companion animals. The diseases discussed in this article do not constitute the entire spectrum of autoimmune disease in these species. They are the common and better-described diseases of dogs and cats that have a well-documented autoimmune etiology. There are myriad autoimmune diseases that affect humans; similar diseases yet unrecognized in companion animals likely will be characterized in the future. The role of genetics in predisposition to autoimmunity is a common characteristic of these diseases in humans and animals. Likewise, the suggested role of environmental or infectious agents is another commonality between humans and their pets.
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