Inflammation processes in perinatal brain damage

J Neural Transm (Vienna). 2010 Aug;117(8):1009-17. doi: 10.1007/s00702-010-0411-x. Epub 2010 May 15.

Abstract

Once viewed as an isolated, immune-privileged organ, the central nervous system has undergone a conceptual change. Neuroinflammation has moved into the focus of research work regarding pathomechanisms underlying perinatal brain damage. In this review, we provide an overview of current concepts regarding perinatal brain damage and the role of inflammation in the disease pathomechanism.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Brain / growth & development
  • Brain / pathology
  • Brain / physiopathology
  • Brain Injuries / complications*
  • Brain Injuries / epidemiology
  • Brain Injuries / immunology
  • Brain Injuries / pathology
  • Developmental Disabilities* / etiology
  • Developmental Disabilities* / immunology
  • Developmental Disabilities* / pathology
  • Humans
  • Inflammation / etiology*
  • Neurons / immunology
  • Premature Birth / physiopathology*