Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 1 (2), 171-4

Synchronous Early Gastric Cancer Resembling Submucosal Tumor at the Fundus

Affiliations

Synchronous Early Gastric Cancer Resembling Submucosal Tumor at the Fundus

Soo Hoon Eun et al. Gut Liver.

Abstract

Concern about detecting gastric carcinoma in its early stages has increased the incidence of detecting multiple synchronous gastric carcinomas. Although gastric carcinomas may present with various gross features, those showing the features of submucosal tumor (SMT) are rare. We report on a case of synchronous gastric carcinomas comprising one lesion with typical features of superficial early gastric carcinoma and the other with atypical features that mimicked SMT. Even though synchronous gastric carcinoma is rare, it may be worthwhile to make a pathological diagnosis of coexisting SMT using endoscopic-ultrasound-guided fine-needle aspiration or endoscopic mucosal resection.

Keywords: Early gastric carcinoma; Submucosal tumor; Synchronous cancer.

Figures

Fig. 1
Fig. 1
Endoscopic view of the tumor showing a covering of normal gastric mucosa and central ulceration.
Fig. 2
Fig. 2
Endoscopic view of the early gastric cancer showing an irregular and slightly raised lesion with central depression.
Fig. 3
Fig. 3
Endoscopic ultrasonography imaging showing a 1.0 cm tumor as a hypoechoic homogeneous mass within the submucosal layer.
Fig. 4
Fig. 4
(A) Low-magnification view of an endoscopic submucosal dissection specimen from the gastric angle, indicating the presence of moderately to poorly differentiated adenocarcinoma confined to the muscularis mucosa (H&E, ×40). (B) Multiple cystic dilatations lined with gastric epithelium are present under the overlying mucosa (H&E, ×160).
Fig. 5
Fig. 5
(A) Whole-mount view of the polypoid mass from the fundus, showing that neoplastic proliferation is confined to the submucosa and that the overlying mucosa is mostly intact except for the periphery near the base (left-lower corner) (H&E, ×14). (B) Microscopic finding of the boxed area in A. The peripheral portion of the mass near the base is a focus of invagination of adenocarcinoma glands into the submucosa (H&E, ×40).

Similar articles

See all similar articles

LinkOut - more resources

Feedback