Marginal zone B-cell orbital lymphoma with intracranial involvement

Ophthalmic Plast Reconstr Surg. May-Jun 2010;26(3):205-6. doi: 10.1097/IOP.0b013e3181b8e0bf.


A 40-year-old woman presented to the eye clinic with painless swelling of her right lower eyelid of 2 years' duration. Examination revealed severe loss of vision in the right eye with hypoglobus and exotropia. CT showed a diffuse right orbital infiltrative lesion with extension to the brain parenchyma. Histopathology confirmed the diagnosis of orbital marginal zone B-cell lymphoma, which is an indolent type of lymphoma that can be associated with systemic lymphoma, but the intracranial association has not been previously described.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Neoplasms / diagnostic imaging
  • Brain Neoplasms / pathology*
  • Female
  • Humans
  • Lymphoma, B-Cell, Marginal Zone / diagnostic imaging
  • Lymphoma, B-Cell, Marginal Zone / pathology*
  • Neoplasm Invasiveness
  • Orbital Neoplasms / diagnostic imaging
  • Orbital Neoplasms / pathology*
  • Tomography, X-Ray Computed