Resonance assignments of myristoylated and non-myristoylated neuronal calcium sensor-1(NCS-1) embedded in a membrane

Kousik Chandra; Venkatesh Ramakrishnan; Yogendra Sharma; K V R Chary

doi:10.1007/s12104-010-9232-y

Resonance assignments of myristoylated and non-myristoylated neuronal calcium sensor-1(NCS-1) embedded in a membrane

Biomol NMR Assign. 2010 Oct;4(2):155-8. doi: 10.1007/s12104-010-9232-y. Epub 2010 May 20.

Authors

Kousik Chandra¹, Venkatesh Ramakrishnan, Yogendra Sharma, K V R Chary

Affiliation

¹ Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai, 400005, India.

PMID: 20490953
DOI: 10.1007/s12104-010-9232-y

Abstract

Neuronal Calcium Sensor-1 (NCS-1) is a member of calcium sensor family. It is originally identified as frequenin. NCS-1 has been found to interact with membrane and cytosolic proteins and its physiological role is governed by N-terminal myristoylation. In this paper, we report the NMR assignments of both myristoylated and non-myristoylated NCS-1 in the presence of a membrane.

MeSH terms

Animals
Membranes, Artificial*
Myristic Acid / metabolism*
Neuronal Calcium-Sensor Proteins / chemistry*
Neuronal Calcium-Sensor Proteins / metabolism*
Neuropeptides / chemistry*
Neuropeptides / metabolism*
Nuclear Magnetic Resonance, Biomolecular*
Rats

Substances

Membranes, Artificial
Neuronal Calcium-Sensor Proteins
Neuropeptides
frequenin calcium sensor proteins
Myristic Acid