Liver transplantation for primary or secondary endocrine tumors

Transpl Int. 2010 Jul;23(7):704-11. doi: 10.1111/j.1432-2277.2010.01110.x. Epub 2010 May 14.


Endocrine tumors comprise a heterogeneous group of rare neoplasms. Liver metastatic endocrine tumors (MET) are amenable to various therapeutic modalities including liver transplantation (LT). However, LT for MET remains controversial because of the lack of clear selection criteria. The purpose of this study based on thorough perusal of English and French literature since 1989 was to identify prognostic factors and propose recommendations for selecting patients most likely to benefit LT for primary and secondary endocrine tumors.

MeSH terms

  • Carcinoma, Hepatocellular / surgery
  • Endocrine Gland Neoplasms / pathology*
  • Endocrine Gland Neoplasms / surgery*
  • Humans
  • Ki-67 Antigen / analysis
  • Liver Neoplasms / secondary
  • Liver Neoplasms / surgery*
  • Liver Transplantation* / mortality
  • Neoplasms, Unknown Primary
  • Neuroendocrine Tumors / secondary
  • Neuroendocrine Tumors / surgery
  • Pancreatic Neoplasms / pathology
  • Pancreatic Neoplasms / surgery
  • Patient Selection
  • Prognosis


  • Ki-67 Antigen