Post-translational modifications in host cells during bacterial infection

FEBS Lett. 2010 Jul 2;584(13):2748-58. doi: 10.1016/j.febslet.2010.05.012. Epub 2010 May 21.


Post-translational modification of proteins is a widespread mechanism used by both prokaryotic and eukaryotic cells to modify the activity of key factors that plays fundamental roles in cellular physiology. This review focuses on how bacterial pathogens can interfere with host post-translational modifications to promote their own survival and replication.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acetylation
  • Animals
  • Bacterial Infections / physiopathology*
  • Glycosylation
  • Host-Pathogen Interactions / physiology
  • Humans
  • Phosphorylation / physiology
  • Protein Processing, Post-Translational / genetics
  • Protein Processing, Post-Translational / physiology*
  • Ubiquitination / physiology