Aging with muscular dystrophy: pathophysiology and clinical management

Phys Med Rehabil Clin N Am. 2010 May;21(2):429-50. doi: 10.1016/j.pmr.2009.12.001.


Major advances in the fields of medical science and physiology, molecular genetics, biomedical engineering, and computer science have provided individuals with muscular dystrophy (MD) with more functional equipment, allowing better strategies for improvement of quality of life. These advances have also allowed a significant number of these patients to live much longer. As progress continues to change management, it also changes patients' expectations. A comprehensive medical and rehabilitative approach to management of aging MD patients can often fulfill expectations and help them enjoy an enhanced quality of life.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Activities of Daily Living
  • Adaptation, Physiological
  • Adolescent
  • Adult
  • Aging / physiology*
  • Child
  • Child, Preschool
  • Combined Modality Therapy
  • Disability Evaluation
  • Disabled Persons*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Muscular Dystrophies / mortality
  • Muscular Dystrophies / physiopathology*
  • Muscular Dystrophies / therapy*
  • Prognosis
  • Quality of Life
  • Risk Assessment
  • Severity of Illness Index
  • Sickness Impact Profile
  • Survival Analysis
  • Treatment Outcome
  • Young Adult