Serous cystadenomas of the pancreas: long-term follow-up measurement of growth rate

Can Assoc Radiol J. 2011 Aug;62(3):190-6. doi: 10.1016/j.carj.2010.04.004. Epub 2010 May 24.

Abstract

Purpose: To measure the growth rate of microcystic subtype serous adenomas of the pancreas diagnosed by imaging.

Methods: For this retrospective study, 241 imaging studies were reviewed from 1998 to 2005. Thirty-one patients met our strict diagnostic imaging inclusion criteria and had at least 18 months of imaging follow-up. Patient demographics and lesion imaging characteristics were tested as predictors of growth.

Results: Growth was measured over a mean period of 42 months. There was a significant (P = .0004) linear growth of tumour for the population. There was significant clustering (P = .001) of the population into 2 growth rates: 0.50 mm/y (n = 23) and 5.5 mm/y (n = 8). The diameter of the lesion at presentation was significantly correlated with growth (r = 0.45; P = .01).

Conclusion: The microcystic subtype of serous cystadenomas of the pancreas diagnosed with imaging criteria demonstrates 2 distinct and slow growth rates. The size of the lesion at presentation is correlated with growth rate.

MeSH terms

  • Adult
  • Comorbidity
  • Contrast Media
  • Cystadenoma, Serous / diagnostic imaging
  • Cystadenoma, Serous / pathology*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Pancreatic Neoplasms / diagnostic imaging
  • Pancreatic Neoplasms / pathology*
  • Retrospective Studies
  • Tomography, Spiral Computed
  • Ultrasonography

Substances

  • Contrast Media