Risk factors for new-onset diabetes after kidney transplantation

Nat Rev Nephrol. 2010 Jul;6(7):415-23. doi: 10.1038/nrneph.2010.66. Epub 2010 May 25.


New-onset diabetes after transplantation, a common complication following kidney transplantation, is associated with adverse patient and graft outcomes. Our understanding of the risk factors associated with this metabolic disorder is improving and both transplantation-specific and nonspecific factors are clearly involved. Knowledge of these risk factors is important so that clinicians can implement pre-emptive risk stratification strategies and to guide therapeutic, risk-attenuation approaches in patients who develop transplant-associated hyperglycemia. In this Review, we explore the current understanding of the diverse range of risk factors that contribute to abnormal glucose metabolism after transplantation, with the aim of helping to guide clinical decision-making using appropriate risk stratification.

Publication types

  • Review

MeSH terms

  • Diabetes Mellitus, Type 2 / epidemiology*
  • Humans
  • Kidney Failure, Chronic / epidemiology*
  • Kidney Failure, Chronic / surgery
  • Kidney Transplantation / statistics & numerical data*
  • Postoperative Complications / epidemiology*
  • Risk Factors