Ultra-wide-field imaging for cytomegalovirus retinitis

Ophthalmic Surg Lasers Imaging. May-Jun 2010;41(3):311-5. doi: 10.3928/15428877-20100430-03.


Background and objective: To compare the Optomap imaging system (Optos PLC, Dunfermline, Scotland) with conventional fundus photography in patients with cytomegalovirus (CMV) retinitis.

Patients and methods: Patients treated at Rush University for acquired immune deficiency syndrome and CMV retinitis were studied prospectively. Conventional nine-field photography and Optomap ultra-wide-field photography were performed on the same day. A patient satisfaction questionnaire was completed. The main outcome measures were total retinal area imaged, area of CMV retinitis imaged, and patient satisfaction.

Results: Twelve eyes met the inclusion criteria. Ultra-wide-field imaging captured 48.3% greater retinal area and 40.0% greater CMV retinitis area compared with standard photography. Standard photography missed peripheral CMV lesions in two eyes. The patient satisfaction survey indicated a preference for ultra-wide-field imaging based on increased comfort and decreased imaging time.

Conclusion: The ultra-wide-field Optomap imaging system tended to capture greater areas of total retina and peripheral CMV retinitis lesions. Patients tended to prefer ultra-wide-field imaging because of the perceived time requirements and comfort of use.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Artifacts
  • Cytomegalovirus Retinitis / diagnosis*
  • Diagnosis, Differential
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Patient Satisfaction
  • Photography / methods*
  • Prospective Studies
  • Reproducibility of Results
  • Retina / pathology*
  • Surveys and Questionnaires