Self-reported Short Sleep Duration and Frequent Snoring in Pregnancy: Impact on Glucose Metabolism

Am J Obstet Gynecol. 2010 Aug;203(2):142.e1-5. doi: 10.1016/j.ajog.2010.03.041. Epub 2010 May 26.

Abstract

Objective: We sought to evaluate the impact of short sleep duration (SSD) and frequent snoring (FS) on glucose metabolism during pregnancy.

Study design: We conducted a prospective cohort study of healthy nulliparas who participated in a sleep survey study. SSD was defined as <7 hours of sleep per night and FS, as snoring >or=3 nights per week. Outcomes included 1-hour oral glucose tolerance results and the presence of gestational diabetes mellitus (GDM). Univariate and multivariate analyses were performed.

Results: A total of 189 women participated; 48% reported an SSD and 18.5% reported FS. SSD and FS were associated with higher oral glucose tolerance values: SSD (116 +/- 31 vs 105 +/- 23; P = .008) and FS (118 +/- 34 vs 108 +/- 25; P = .04). Both SSD (10.2% vs 1.1%; P = .008) and FS (14.3% vs 3.3%; P = .009) were associated with a higher incidence of GDM. Even after controlling for potential confounders, SSD and FS remained associated with GDM.

Conclusion: SSD and FS are associated with glucose intolerance in pregnancy.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Age Distribution
  • Blood Glucose / analysis*
  • Cohort Studies
  • Comorbidity
  • Confidence Intervals
  • Diabetes, Gestational / diagnosis
  • Diabetes, Gestational / epidemiology*
  • Female
  • Follow-Up Studies
  • Gestational Age
  • Glucose / metabolism*
  • Glucose Intolerance
  • Glucose Tolerance Test / methods
  • Humans
  • Logistic Models
  • Multivariate Analysis
  • Pregnancy
  • Pregnancy Outcome
  • Prenatal Care / methods
  • Prenatal Diagnosis
  • Prevalence
  • Probability
  • Prospective Studies
  • Risk Assessment
  • Self Disclosure
  • Sleep Wake Disorders / diagnosis
  • Sleep Wake Disorders / epidemiology*
  • Snoring / diagnosis
  • Snoring / epidemiology*
  • Young Adult

Substances

  • Blood Glucose
  • Glucose