Is there a benefit to the treatment of mild gestational diabetes mellitus?

Am J Obstet Gynecol. 2010 Jun;202(6):649-53. doi: 10.1016/j.ajog.2010.02.006.

Abstract

Despite widespread acceptance of the value of screening for and treating gestational diabetes mellitus (GDM) in the United States, evidence concerning a benefit to this approach has been lacking. Confounding variables have specifically raised the question as to whether mild forms of carbohydrate intolerance are associated with increased perinatal and maternal risks. The findings of 2 recently conducted large-scale randomized clinical trials both indicate significant reductions in fetal overgrowth, shoulder dystocia, and preeclampsia with treatment. Thus, compelling evidence now exists that the benefit outweighs risks associated with the treatment of mild GDM.

Publication types

  • Review

MeSH terms

  • Diabetes, Gestational / drug therapy*
  • Female
  • Glucose Tolerance Test
  • Humans
  • Hyperglycemia / drug therapy*
  • Hypoglycemic Agents / therapeutic use
  • Insulin / therapeutic use
  • Pregnancy
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Hypoglycemic Agents
  • Insulin