Reproductive outcome following hysteroscopic myomectomy in patients with infertility and recurrent abortions

Arch Gynecol Obstet. 2010 Nov;282(5):553-60. doi: 10.1007/s00404-010-1531-0. Epub 2010 May 30.

Abstract

Objectives: To evaluate the outcome of hysteroscopic myomectomy in patients with infertility and recurrent abortions.

Materials and methods: This was a retrospective clinical analysis of 186 patients who underwent hysteroscopic myomectomy by monopolar electrode loop. A second-look diagnostic hysteroscopy was performed in all cases within 2 months. The mean follow-up period was 36.5 months.

Results: The mean age of the patients was 28.4 years. The presenting clinical complaint was primary infertility in 31% (62/200) patients, secondary infertility in 10% (20/200) patients, recurrent abortions in 50.5% (101/200) and preterm deliveries in 8.5% (17/200) patients. Final reproductive outcome was assessed for 186 patients, after excluding patients with other confounding factors, interfering in pregnancy outcome. There was a significant difference in reduction of number of miscarriages and increase in term deliveries while the number of preterm deliveries remained almost the same. Fifty-eight out of 82 infertile patients (70.7%) conceived after hysteroscopic myomectomy. The take home baby rate was increased from 16.2 to 74%. There was an increased incidence (35.6%) of cesarean section recorded in mode of delivery.

Conclusion: Hysteroscopic myomectomy is a safe and effective method for improving the obstetric outcome in women with infertility and recurrent abortions and associated submucous fibroids.

MeSH terms

  • Abortion, Habitual / prevention & control
  • Abortion, Habitual / surgery
  • Abortion, Habitual / therapy*
  • Adult
  • Female
  • Humans
  • Hysteroscopy / methods*
  • Hysteroscopy / standards
  • Infertility, Female / prevention & control
  • Infertility, Female / surgery
  • Infertility, Female / therapy*
  • Leiomyoma / surgery*
  • Pregnancy
  • Pregnancy Outcome
  • Retrospective Studies