A central role for p38 MAPK in the early transcriptional response to stress

BMC Biol. 2010 Apr 27;8:47. doi: 10.1186/1741-7007-8-47.

Abstract

The mitogen-activated protein kinase p38 (p38 MAPK) is activated by a number of stresses. A recent study in BMC Genomics has uncovered the early transcriptional responses to three types of stress and has demonstrated a central role for p38 MAPK in mediating these responses. See research article http://www.biomedcentral.com/1471-2164/11/144.

Publication types

  • Comment
  • Editorial

MeSH terms

  • Gene Expression Regulation / physiology*
  • Humans
  • Signal Transduction / physiology*
  • Stress, Physiological / physiology*
  • p38 Mitogen-Activated Protein Kinases / metabolism*

Substances

  • p38 Mitogen-Activated Protein Kinases