Low incidence of post-lumbar puncture headache in 1,089 consecutive memory clinic patients

Eur Neurol. 2010;63(6):326-30. doi: 10.1159/000311703. Epub 2010 Jun 3.


Aim: To examine the incidence of post-lumbar puncture headache (PLPH) in patients admitted for cognitive disturbances.

Methods: The incidence of PLPH and other general (subdural hematoma, meningitis, encephalitis) or local (local pain, spinal hematoma, local infection) complications was evaluated in 1,089 consecutive patients (aged 23-89 years) who underwent lumbar puncture as a part of the routine diagnostic evaluation between February 2001 and March 2007 at a specialized memory clinic.

Results: 28 (2.6%) of the patients reported PLPH of mild severity. No other local or general complications occurred.

Conclusions: The incidence of PLPH in patients with cognitive disturbances is low and CSF analyses can thus be part of the diagnostic work-up at memory clinics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cohort Studies
  • Female
  • Humans
  • Male
  • Memory Disorders / cerebrospinal fluid*
  • Memory Disorders / diagnosis
  • Mental Status Schedule
  • Middle Aged
  • Post-Dural Puncture Headache / diagnosis*
  • Post-Dural Puncture Headache / etiology*
  • Retrospective Studies
  • Spinal Puncture / adverse effects*
  • Statistics, Nonparametric
  • Young Adult