Risk factors for severe complications of the novel influenza A (H1N1): analysis of patients hospitalized in Italy

Clin Microbiol Infect. 2011 Feb;17(2):247-50. doi: 10.1111/j.1469-0691.2010.03275.x.

Abstract

Eighty-one patients affected by the novel influenza A (H1N1), hospitalized in North-western Italy, were studied. The median age was 32 years (range 1-81 years). Fifty-six (69%) had an underlying medical condition, including lung disorders (asthma or chronic obstructive pulmonary disease) in 34% and obesity in 25%. Fifty percent of them had pneumonia, 12% were admitted to the intensive care unit and 3% died. Antiviral treatment was initiated in 75% of patients started within 48 h. Older age and lung and neurocognitive disorders were associated with severe disease and death.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Critical Care
  • Female
  • Humans
  • Infant
  • Influenza A Virus, H1N1 Subtype / isolation & purification*
  • Influenza, Human / complications*
  • Influenza, Human / epidemiology*
  • Influenza, Human / mortality
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Pneumonia / epidemiology
  • Pregnancy
  • Prevalence
  • Risk Factors
  • Young Adult