Ontologies in quantitative biology: a basis for comparison, integration, and discovery

PLoS Biol. 2010 May 25;8(5):e1000374. doi: 10.1371/journal.pbio.1000374.


As biology is becoming a data-driven discipline, ontologies become increasingly important for systematically capturing the existing knowledge. This essay discusses current trends and how ontologies can also be used for discovery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biomedical Research* / classification
  • Biomedical Research* / methods
  • Computational Biology / methods
  • Databases, Factual
  • Genomics
  • Humans
  • Molecular Biology* / classification
  • Molecular Biology* / methods
  • Terminology as Topic*
  • Vocabulary, Controlled