CCancer: a bird's eye view on gene lists reported in cancer-related studies

Nucleic Acids Res. 2010 Jul;38(Web Server issue):W118-23. doi: 10.1093/nar/gkq515. Epub 2010 Jun 6.

Abstract

CCancer is an automatically collected database of gene lists, which were reported mostly by experimental studies in various biological and clinical contexts. At the moment, the database covers 3369 gene lists extracted from 2644 papers published in approximately 80 peer-reviewed journals. As input, CCancer accepts a gene list. An enrichment analyses is implemented to generate, as output, a highly informative survey over recently published studies that report gene lists, which significantly intersect with the query gene list. A report on gene pairs from the input list which were frequently reported together by other biological studies is also provided. CCancer is freely available at http://mips.helmholtz-muenchen.de/proj/ccancer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aniline Compounds / therapeutic use
  • Cellular Senescence / genetics
  • Data Mining
  • Databases, Genetic*
  • Gene Expression Regulation, Neoplastic
  • Genes, Neoplasm*
  • Humans
  • Internet
  • Monte Carlo Method
  • Neoplasm Proteins / genetics
  • Neoplasms / genetics*
  • Nitriles / therapeutic use
  • Protein Kinase Inhibitors / therapeutic use
  • Quinolines / therapeutic use
  • Software*

Substances

  • Aniline Compounds
  • Neoplasm Proteins
  • Nitriles
  • Protein Kinase Inhibitors
  • Quinolines
  • bosutinib