Effects of acute, graded compression on spinal nerve root function and structure. An experimental study of the pig cauda equina

Spine (Phila Pa 1976). 1991 May;16(5):487-93. doi: 10.1097/00007632-199105000-00001.


A well-controlled experimental model for analysis of compression-induced functional changes of the porcine cauda equina is presented. The model allows for electrophysiologic investigation of a variety of neurophysiologic changes induced by nerve root deformation. At an acute pressure threshold of 50-75 mm Hg, changes in both afferent and efferent conduction are induced. With higher compression pressure, a differential recovery in afferent and efferent conduction is seen.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Action Potentials / physiology
  • Afferent Pathways / physiology
  • Animals
  • Cauda Equina / pathology
  • Cauda Equina / physiopathology*
  • Efferent Pathways / physiology
  • Electromyography
  • Nerve Compression Syndromes / pathology
  • Nerve Compression Syndromes / physiopathology*
  • Neural Conduction / physiology
  • Pressure
  • Sensory Receptor Cells / physiology
  • Swine