Tonsillectomy and adenoidectomy for obstructive sleep apnea in sickle cell anemia

Indian J Pediatr. 2010 Jun;77(6):669-72. doi: 10.1007/s12098-010-0093-2. Epub 2010 Jun 8.


Objective: To evaluate the effects of Tonsillectomy and Adenoidectomy (T&A) on Obstructive Sleep Apnea (OSA) secondary to Upper Airway Obstruction (UAO) in children with Sickle Cell Disease (SCD).

Methods: Twenty eight children with SCD and history of snoring, with or without adeno tonsillar hypertrophy, were evaluated for UAO and OSA.

Results: Eight children were confirmed to have OSA by multichannel polysomnography and underwent T&A. Follow up examination showed symptomatic clinical and objective improvement in sleep study parameters in OSA.

Conclusions: T&A appears to be a safe, effective option to treat selected patients with OSA due to UAO in SCD children.

MeSH terms

  • Adenoidectomy*
  • Adolescent
  • Anemia, Sickle Cell / complications
  • Anemia, Sickle Cell / diagnosis
  • Anemia, Sickle Cell / surgery*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Quality of Life
  • Retrospective Studies
  • Sleep Apnea, Obstructive / complications
  • Sleep Apnea, Obstructive / diagnosis
  • Sleep Apnea, Obstructive / surgery*
  • Tonsillectomy*
  • Treatment Outcome