Focal neuromyotonia: do I love you?

J Neurol. 2010 Oct;257(10):1727-9. doi: 10.1007/s00415-010-5612-6. Epub 2010 Jun 9.


We present a rare case of focal neuromyotonia in a 73-year-old woman with a follow up of 5 years. The clinical picture showed a fixed contraction of the 3rd and 4th finger of the left hand. Similar to other published cases, our patient suffered from COPD and was treated with beta-2-sympathomimetics. This clinical picture shows a rare but rather salient differential diagnosis of Dupuytren's contracture. EMG of the affected muscles may yield a diagnosis and prevent the patient from a long and ineffective treatment "odyssey".

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Diagnosis, Differential
  • Electromyography
  • Female
  • Fingers / physiopathology*
  • Humans
  • Isaacs Syndrome* / pathology
  • Isaacs Syndrome* / physiopathology
  • Longitudinal Studies
  • Pulmonary Disease, Chronic Obstructive / complications
  • Pulmonary Disease, Chronic Obstructive / diagnosis
  • Pulmonary Disease, Chronic Obstructive / drug therapy