Abstract
In this article, abnormalities in the proliferation and differentiation of gastrointestinal cells are described in diseases that increase predisposition to gastrointestinal cancer. Recent findings related to the effects of calcium on gastrointestinal cell proliferation, differentiation, and tumor occurrence in rodent models and in human subjects are summarized.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Biomarkers
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Digestive System / pathology*
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Epithelium / pathology
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Esophageal Diseases / complications
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Esophageal Diseases / pathology
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Gastrointestinal Diseases / complications
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Gastrointestinal Diseases / pathology*
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Gastrointestinal Neoplasms / etiology
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Gastrointestinal Neoplasms / prevention & control*
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Humans
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Hyperplasia
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Intestinal Diseases / complications
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Intestinal Diseases / pathology
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Stomach Diseases / complications
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Stomach Diseases / pathology