Hemorrhagic, bullous Henoch Schonlein purpura in a 16-year-old girl with previously undiagnosed dominant dystrophic epidermolysis bullosa

Pediatr Dermatol. Mar-Apr 2010;27(2):203-4. doi: 10.1111/j.1525-1470.2010.01105.x.

Abstract

A 16-year-old girl presenting with systemic and cutaneous symptoms of hemorrhagic Henoch-Schonlein purpura continued to develop bullae on top of old scars. Past history was significant for bullae on the feet and legs after trauma. Based on history, physical examination, disease course, and biopsy, the patient, her mother, and other family members were diagnosed with dominant dystrophic epidermolysis bullosa, explaining the severe course and complications of her Henoch-Schonlein purpura.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Blister / diagnosis
  • Blister / genetics
  • Epidermolysis Bullosa Dystrophica / diagnosis*
  • Epidermolysis Bullosa Dystrophica / drug therapy
  • Epidermolysis Bullosa Dystrophica / genetics
  • Female
  • Hemorrhage / diagnosis
  • Hemorrhage / genetics
  • Humans
  • Immunoglobulin A / analysis
  • Prednisone / therapeutic use
  • Purpura, Schoenlein-Henoch / diagnosis*
  • Purpura, Schoenlein-Henoch / drug therapy
  • Purpura, Schoenlein-Henoch / genetics

Substances

  • Immunoglobulin A
  • Prednisone