Abstract
Temozolomide, an oral alkylating agent, is a commonly used medicine in the treatment of anaplastic astrocytoma and glioblastoma multiforme. This paper will present the mechanism of action as well as the clinical role for this chemotherapeutic drug.
MeSH terms
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Administration, Oral
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Antineoplastic Agents, Alkylating / administration & dosage*
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Antineoplastic Agents, Alkylating / adverse effects
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Antineoplastic Agents, Alkylating / economics
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Astrocytoma / drug therapy*
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Brain Neoplasms / drug therapy*
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Dacarbazine / administration & dosage
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Dacarbazine / adverse effects
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Dacarbazine / analogs & derivatives*
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Dacarbazine / economics
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Drug Costs
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Glioblastoma / drug therapy*
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Humans
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Temozolomide
Substances
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Antineoplastic Agents, Alkylating
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Dacarbazine
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Temozolomide