Small cytokine superfamily

Curr Opin Immunol. 1991 Feb;3(1):56-60. doi: 10.1016/0952-7915(91)90077-e.

Abstract

Proteins comprising a newly described superfamily of small inducible cytokines (tentatively designated 'scy') exhibit considerable similarity with respect to activity, regulation and genomic structure. Recent observations, however, have identified specific biological activities and contexts in which these cytokines differ and which may allow fine tuning of immune and inflammatory responses.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Chemokine CCL2
  • Chemokine CCL4
  • Chemokine CXCL2
  • Chemotactic Factors / immunology
  • Cytokines / biosynthesis
  • Cytokines / immunology*
  • Hematopoiesis / physiology
  • Humans
  • Inflammation / immunology
  • Interleukin-8 / immunology
  • Macrophage Inflammatory Proteins
  • Mice
  • Monokines / immunology
  • Transcription, Genetic

Substances

  • Chemokine CCL2
  • Chemokine CCL4
  • Chemokine CXCL2
  • Chemotactic Factors
  • Cytokines
  • Interleukin-8
  • Macrophage Inflammatory Proteins
  • Monokines