Transport at the Recycling Endosome

Curr Opin Cell Biol. 2010 Aug;22(4):528-34. doi: 10.1016/j.ceb.2010.05.008. Epub 2010 Jun 11.

Abstract

The recycling endosome (RE) has long been considered as a sub-compartment of the early endosome that recycles internalized cargoes to the plasma membrane. The RE is now appreciated to participate in a more complex set of intracellular itineraries. Key cargo molecules and transport factors that act in these pathways are being identified. These advancements are beginning to reveal complexities in pathways involving the RE, and also suggest ways of further delineating functional domains of this compartment.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Biological Transport
  • Coated Vesicles / metabolism
  • Endocytosis*
  • Endosomes / metabolism*
  • Humans
  • SNARE Proteins / metabolism
  • rab GTP-Binding Proteins / metabolism

Substances

  • SNARE Proteins
  • rab GTP-Binding Proteins