MRI safety: nephrogenic systemic fibrosis and other risks

J Clin Neurosci. 2010 Sep;17(9):1097-104. doi: 10.1016/j.jocn.2010.01.016. Epub 2010 Jun 12.


Magnetic resonance imaging (MRI) is now a commonly used imaging modality in many neurosurgical and neurological conditions. Although generally regarded as safe, there are a number of important safety considerations. These include a recently recognised, rare condition termed nephrogenic systemic fibrosis (NSF) that occurs in patients with significant renal impairment who receive gadolinium based contrast. Currently, NSF remains poorly understood and there is no universally effective treatment beyond the avoidance of contrast in patients with significant renal impairment. Other safety considerations include MRI contraindicated devices and the role of MRI in pregnancy.

Publication types

  • Review

MeSH terms

  • Humans
  • Kidney Diseases* / complications
  • Kidney Diseases* / diagnosis
  • Magnetic Resonance Imaging / adverse effects*
  • Nephrogenic Fibrosing Dermopathy / diagnosis*
  • Nephrogenic Fibrosing Dermopathy / etiology*
  • Nephrogenic Fibrosing Dermopathy / prevention & control
  • Risk Factors