Lifetime depression and diabetes self-management in women with Type 2 diabetes: a case-control study

Diabet Med. 2010 Jun;27(6):713-7. doi: 10.1111/j.1464-5491.2010.02996.x.


Aims: Little is known about the association between lifetime history of major depressive disorder (L-MDD) and diabetes self-management, particularly when depression is remitted. We examined the association between L-MDD and diabetes self-management in women with Type 2 diabetes who were not depressed at the time of assessment.

Methods: L-MDD was assessed with structured psychiatric interview. Participants completed paper-and-pencil measures of demographics, diabetes-related distress, self-care behaviours, healthcare utilization and diabetes self-efficacy.

Results: One-hundred and fifty-three women participated; 41% had L-MDD. Compared with their never-depressed counterparts, women with L-MDD had more diabetes distress, reported lower overall rates of self-monitoring of blood glucose (SMBG) and greater tendency to skip SMBG, had lower diet adherence and were less likely to have seen a primary care provider in the past year. Diabetes self-efficacy mediated the relationship between L-MDD and self-management.

Conclusions: Interventions to promote self-management for patients with L-MDD may be warranted.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Analysis of Variance
  • Blood Glucose Self-Monitoring / psychology
  • Case-Control Studies
  • Depressive Disorder / complications
  • Depressive Disorder / psychology*
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / drug therapy
  • Diabetes Mellitus, Type 2 / psychology*
  • Female
  • Humans
  • Hypoglycemic Agents / administration & dosage*
  • Middle Aged
  • Patient Compliance / psychology*
  • Self Care / psychology*
  • Self Efficacy
  • Severity of Illness Index
  • Socioeconomic Factors
  • Time Factors


  • Hypoglycemic Agents