Right ventricle-sparing left ventricular resection and replacement with a continuous-flow rotary blood pump: an in vivo experiment

Tex Heart Inst J. 2010;37(3):276-9.

Abstract

Despite recent advances in left ventricular assist device and total artificial heart technologies, these devices are still so large that they pose a significant problem in small patients with refractory heart failure. Excising the left ventricle while preserving the right ventricle--and then replacing the left ventricle with a mechanical pump--has been proposed as an alternative approach to this problem. We conducted a pilot study to evaluate possible surgical techniques and the hemodynamic effects of right ventricle-sparing left ventricular resection and replacement with a continuous-flow rotary blood pump in a healthy bovine model.

Keywords: Animals; blood pump, centrifugal; heart failure, congestive; heart transplantation; heart ventricles; heart, artificial; heart-assist devices; prosthesis fitting; prosthesis implantation.

MeSH terms

  • Animals
  • Cardiac Surgical Procedures / instrumentation*
  • Cattle
  • Heart Ventricles / physiopathology
  • Heart Ventricles / surgery*
  • Heart-Assist Devices*
  • Hemodynamics*
  • Materials Testing
  • Models, Animal
  • Pilot Projects
  • Prosthesis Design
  • Time Factors
  • Ventricular Function, Left*
  • Ventricular Function, Right*