Indications for penetrating keratoplasty: 1980-1988

Cornea. 1991 May;10(3):210-6. doi: 10.1097/00003226-199105000-00005.

Abstract

A retrospective analysis was undertaken of the clinical diagnoses of 1594 eyes that underwent penetrating keratoplasty performed in a private-referral corneal practice over a 9-year period, 1980-1988. The seven most common indications for surgery were keratoconus (24.0%), pseudophakic or aphakic bullous keratopathy (21.2%), corneal scarring (13.9%), Fuchs' endothelial dystrophy (12.5%), regraft (8.1%), and herpetic keratitis (5.3%). Keratoconus was the leading indication from 1980 to 1985. From 1985 to 1988, pseudophakic bullous keratopathy became the leading indication and correlates well with known complications associated with closed-loop anterior chamber lenses, which were widely used during the early 1980s. Less frequent indications for penetrating keratoplasty included the following: infectious (nonviral) keratitis (3.5%); acute or chronic ulcerative keratitis (2.7%); interstitial keratitis (1.8%); mechanical trauma (1.5%); other (non-Fuchs') corneal dystrophies (1.4%); congenital opacities (0.8%); and chemical burns (0.5%).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aphakia / surgery
  • Corneal Diseases / diagnosis
  • Corneal Diseases / surgery*
  • Fuchs' Endothelial Dystrophy / surgery
  • Humans
  • Incidence
  • Keratitis, Dendritic / surgery
  • Keratoconus / surgery
  • Keratoplasty, Penetrating*
  • Lenses, Intraocular
  • Preoperative Care
  • Reoperation
  • Retrospective Studies