Chemical composition and antibacterial activity of essential oil of Heracleum rechingeri Manden from Iran

Nat Prod Res. 2010 Jul;24(11):1013-7. doi: 10.1080/14786410902885138.

Abstract

The chemical composition of the essential oil from Heracleum rechingeri was analysed using GC-MS. Twenty-seven compounds, accounting for 94.62% of the extracted essential oil, were identified. The main oil compounds were octyl acetate (29.49%), elemicine (23.06%), (E)-caryophyllene (9.26%), caryophyllene oxide (6.42%), terpinolene (6.12%) and (Z)-3-octenyl acetate (4.72%). The antimicrobial activity of the essential oil was tested against three different bacteria by disc diffusion method and showed maximum inhibitory activity against Gram-positive bacteria, especially Bacillus subtilis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetates / chemistry
  • Acetates / pharmacology
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Cyclohexane Monoterpenes
  • Gas Chromatography-Mass Spectrometry
  • Heracleum / chemistry*
  • Iran
  • Microbial Sensitivity Tests
  • Oils, Volatile / chemistry
  • Oils, Volatile / pharmacology*
  • Polycyclic Sesquiterpenes
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / pharmacology
  • Staphylococcus aureus / drug effects
  • Terpenes / chemistry
  • Terpenes / pharmacology

Substances

  • Acetates
  • Anti-Bacterial Agents
  • Cyclohexane Monoterpenes
  • Oils, Volatile
  • Polycyclic Sesquiterpenes
  • Sesquiterpenes
  • Terpenes
  • caryophyllene
  • terpinolene
  • caryophyllene oxide
  • octyl acetate