[Effects of chronic exposure of power frequency magnetic field on neurobehavior in rats]

Beijing Da Xue Xue Bao Yi Xue Ban. 2010 Jun 18;42(3):351-5.
[Article in Chinese]


Objective: To observe the effect of chronic exposure to extremely low frequency magnetic field on neurobehavioral of adult rats.

Methods: Fifty Hz sinusoidal extremely low frequency magnetic field (ELF-MF) was used in this experimental procedure and the strength of magnetic field was fixed at 2 mT. Thirty male adult rats were divided randomly into 3 groups: (1) no ELF MF exposure (control group, n=10); (2) exposure to ELF MF 1 h/day (MF1h group, n=10); (3) exposure to ELF MF 4 h/day (MF4h group, n=10). The neurobehavioral changes of rats were detected by the open field test, elevated plus maze test and light/dark box test.

Results: Compared with controls, no significant difference was found in rats of MF1h group in any test. Rats in MF4h group showed increased thigmotaxis, more grooming in the open field test; less time spent in open arms, central part and more time spent in closed arms. However, no significant difference was observed in the light/dark test in MF1h or MF4h group.

Conclusion: Chronic ELF MF exposure has an anxiogenic effect on rats, which is dependent on the daily exposure duration.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anxiety Disorders / etiology*
  • Anxiety Disorders / physiopathology
  • Behavior, Animal / physiology
  • Behavior, Animal / radiation effects*
  • Brain / physiopathology
  • Brain / radiation effects
  • Electromagnetic Fields / adverse effects*
  • Environmental Exposure*
  • Male
  • Motor Activity / physiology
  • Motor Activity / radiation effects
  • Psychomotor Performance / radiation effects
  • Random Allocation
  • Rats
  • Rats, Sprague-Dawley