Biofilm formation and genotyping of Candida haemulonii, Candida pseudohaemulonii, and a proposed new species (Candida auris) isolates from Korea

Med Mycol. 2011 Jan;49(1):98-102. doi: 10.3109/13693786.2010.493563. Epub 2010 Jun 21.


Emergence of Candida haemulonii and closely related species at five Korean hospitals has been recently described. We examined biofilm formation by these isolates and assessed their genotypic relatedness by pulsed-field gel electrophoresis (PFGE). This study is the first to show that all bloodstream isolates of Candida pseudohaemulonii can form significant biofilms in glucose-containing medium. PFGE of NotI-digested genomic DNA revealed that C. pseudohaemulonii isolates recovered from seven patients in two hospitals shared five patterns, and that 15 isolates of a proposed new species (Candida auris) obtained from patients at three hospitals shared seven patterns, suggesting that some of these isolates may be related to clonal transmission.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biofilms / growth & development*
  • Blood / microbiology
  • Candida / classification*
  • Candida / genetics
  • Candida / isolation & purification
  • Candida / physiology*
  • Candidiasis / microbiology*
  • Cluster Analysis
  • Culture Media / chemistry
  • Electrophoresis, Gel, Pulsed-Field
  • Genotype
  • Humans
  • Molecular Typing
  • Mycological Typing Techniques
  • Republic of Korea


  • Culture Media