Assemble: an interactive graphical tool to analyze and build RNA architectures at the 2D and 3D levels

Bioinformatics. 2010 Aug 15;26(16):2057-9. doi: 10.1093/bioinformatics/btq321. Epub 2010 Jun 18.


Summary: Assemble is an intuitive graphical interface to analyze, manipulate and build complex 3D RNA architectures. It provides several advanced and unique features within the framework of a semi-automated modeling process that can be performed by homology and ab initio with or without electron density maps. Those include the interactive editing of a secondary structure and a searchable, embedded library of annotated tertiary structures. Assemble helps users with performing recurrent and otherwise tedious tasks in structural RNA research.

Availability and implementation: Assemble is released under an open-source license (MIT license) and is freely available at It is implemented in the Java language and runs on MacOSX, Linux and Windows operating systems.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computational Biology
  • Computer Graphics*
  • Models, Molecular
  • Nucleic Acid Conformation
  • RNA / chemistry*
  • Sequence Analysis, RNA
  • Software*
  • User-Computer Interface


  • RNA