Effect of Artocarpus heterophyllus and Asteracanthus longifolia on glucose tolerance in normal human subjects and in maturity-onset diabetic patients

J Ethnopharmacol. 1991 Mar;31(3):277-82. doi: 10.1016/0378-8741(91)90012-3.


Investigations were carried out to evaluate the effects of hot-water extracts of Artocarpus heterophyllus leaves and Asteracanthus longifolia whole plant material on the glucose tolerance of normal human subjects and maturity-onset diabetic patients. The extracts of both Artocarpus heterophyllus and Asteracanthus longifolia significantly improved glucose tolerance in the normal subjects and the diabetic patients when investigated at oral doses equivalent to 20 g/kg of starting material.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Glucose / metabolism
  • Diabetes Mellitus, Type 2 / metabolism*
  • Glucose Tolerance Test*
  • Humans
  • Hypoglycemic Agents*
  • Male
  • Middle Aged
  • Plant Extracts / pharmacology*
  • Plants, Medicinal / analysis*
  • Sri Lanka


  • Blood Glucose
  • Hypoglycemic Agents
  • Plant Extracts