Two-headed PROTAC: an effective new tool for targeted protein degradation

Chembiochem. 2010 Jul 26;11(11):1531-4. doi: 10.1002/cbic.201000222.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drug Delivery Systems
  • Female
  • Humans
  • Intercellular Signaling Peptides and Proteins
  • Ligases
  • Peptides / pharmacology*
  • Protein Stability / drug effects
  • Proteins / drug effects
  • Proteins / metabolism*
  • Receptors, Estrogen / drug effects
  • Receptors, Estrogen / metabolism*

Substances

  • Intercellular Signaling Peptides and Proteins
  • Peptides
  • Proteins
  • Receptors, Estrogen
  • snake venom protein C activator
  • Ligases