HLA alleles and fissured tongue

Int J Immunogenet. 2010 Dec;37(6):509-11. doi: 10.1111/j.1744-313X.2010.00944.x.

Abstract

The aim of this study was to investigate the linkage between HLA and fissured tongue. Sixty- nine individuals with fissured tongue and 125 healthy volunteers were typed for HLA-DRB1*. The results showed increased frequency of HLA-DRB1*08 (P < 0.001), HLA-DRB1*14 (P < 0.01), HLA-DRB1*11 (P < 0.05) and HLA-DRB1*16 (P < 0.05), while HLA-DRB1*03 and HLA-DRB1*07 frequency was decreased (P < 0.05).

MeSH terms

  • Alleles
  • Chi-Square Distribution
  • Female
  • Gene Frequency
  • Genes, Dominant
  • Genetic Linkage*
  • Genetic Predisposition to Disease*
  • Greece
  • HLA Antigens / genetics
  • HLA-DR Antigens / genetics*
  • HLA-DRB1 Chains
  • Haplotypes
  • Histocompatibility Testing
  • Humans
  • Male
  • Polymerase Chain Reaction
  • Tongue, Fissured / genetics*

Substances

  • HLA Antigens
  • HLA-DR Antigens
  • HLA-DRB1 Chains