Micronutrient quality of weight-loss diets that focus on macronutrients: results from the A TO Z study

Am J Clin Nutr. 2010 Aug;92(2):304-12. doi: 10.3945/ajcn.2010.29468. Epub 2010 Jun 23.

Abstract

Background: Information on the micronutrient quality of alternative weight-loss diets is limited, despite the significant public health relevance.

Objective: Micronutrient intake was compared between overweight or obese women randomly assigned to 4 popular diets that varied primarily in macronutrient distribution.

Design: Dietary data were collected from women in the Atkins (n = 73), Zone (n = 73), LEARN (Lifestyle, Exercise, Attitudes, Relationships, Nutrition) (n = 73), and Ornish (n = 72) diet groups by using 3-d, unannounced 24-h recalls at baseline and after 8 wk of instruction. Nutrient intakes were compared between groups at 8 wk and within groups for 8-wk changes in risk of micronutrient inadequacy.

Results: At 8 wk, significant differences were observed between groups for all macronutrients and for many micronutrients (P < 0.0001). Energy intake decreased from baseline in all 4 groups but was similar between groups. At 8 wk, a significant proportion of individuals shifted to intakes associated with risk of inadequacy (P < 0.05) in the Atkins group for thiamine, folic acid, vitamin C, iron, and magnesium; in the LEARN group for vitamin E, thiamine, and magnesium; and in the Ornish group for vitamins E and B-12 and zinc. In contrast, for the Zone group, the risk of inadequacy significantly decreased for vitamins A, E, K, and C (P < 0.05), and no significant increases in risk of inadequacy were observed for other micronutrients.

Conclusions: Weight-loss diets that focus on macronutrient composition should attend to the overall quality of the diet, including the adequacy of micronutrient intakes. Concerning calorie-restricted diets, there may be a micronutrient advantage to diets providing moderately low carbohydrate amounts and that contain nutrient-dense foods.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anemia, Iron-Deficiency / etiology
  • Avitaminosis / etiology
  • Deficiency Diseases / etiology*
  • Diet, Reducing* / adverse effects
  • Diet, Reducing* / classification
  • Diet, Reducing* / standards
  • Energy Intake*
  • Female
  • Humans
  • Magnesium Deficiency / etiology
  • Micronutrients / administration & dosage*
  • Middle Aged
  • Risk Factors

Substances

  • Micronutrients