Higher prevalence of pharyngeal than nasal Staphylococcus aureus carriage in pediatric intensive care units

doi:10.1128/JCM.00547-10

Comparative Study

. 2010 Aug;48(8):2957-9.

doi: 10.1128/JCM.00547-10. Epub 2010 Jun 23.

Higher prevalence of pharyngeal than nasal Staphylococcus aureus carriage in pediatric intensive care units

Mari M Nakamura¹, Alexander J McAdam, Thomas J Sandora, Katharina R Moreira, Grace M Lee

Affiliations

PMID: 20573867
PMCID: PMC2916627
DOI: 10.1128/JCM.00547-10

Comparative Study

Higher prevalence of pharyngeal than nasal Staphylococcus aureus carriage in pediatric intensive care units

Mari M Nakamura et al. J Clin Microbiol. 2010 Aug.

. 2010 Aug;48(8):2957-9.

doi: 10.1128/JCM.00547-10. Epub 2010 Jun 23.

Authors

Mari M Nakamura¹, Alexander J McAdam, Thomas J Sandora, Katharina R Moreira, Grace M Lee

Affiliation

¹ Division of Infectious Diseases, Department of Medicine, Children's Hospital Boston, Boston, MA, USA. mari.nakamura@childrens.harvard.edu

PMID: 20573867
PMCID: PMC2916627
DOI: 10.1128/JCM.00547-10

Abstract

Sensitive detection of Staphylococcus aureus colonization is important for epidemiologic studies, infection control, and decolonization measures. We examined the sensitivity of nasal and pharyngeal sampling for S. aureus colonization in 331 children admitted to intensive care units. Pharyngeal screening was more sensitive than nasal screening (92.6% versus 63.1%, P < 0.0001).

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References

1. Armstrong-Esther, C. A. 1976. Carriage patterns of Staphylococcus aureus in a healthy non-hospital population of adults and children. Ann. Hum. Biol. 3:221-227. - PubMed
1. Blot, S. I., K. H. Vandewoude, E. A. Hoste, and F. A. Colardyn. 2002. Outcome and attributable mortality in critically ill patients with bacteremia involving methicillin-susceptible and methicillin-resistant Staphylococcus aureus. Arch. Intern. Med. 162:2229-2235. - PubMed
1. Burke, R. E., M. S. Halpern, E. J. Baron, and K. Gutierrez. 2009. Pediatric and neonatal Staphylococcus aureus bacteremia: epidemiology, risk factors, and outcome. Infect. Control Hosp. Epidemiol. 30:636-644. - PubMed
1. Coello, R., J. Jimenez, M. Garcia, P. Arroyo, D. Minguez, C. Fernandez, F. Cruzet, and C. Gaspar. 1994. Prospective study of infection, colonization and carriage of methicillin-resistant Staphylococcus aureus in an outbreak affecting 990 patients. Eur. J. Clin. Microbiol. Infect. Dis. 13:74-81. - PubMed
1. Cox, R. A., C. Conquest, C. Mallaghan, and R. R. Marples. 1995. A major outbreak of methicillin-resistant Staphylococcus aureus caused by a new phage-type (EMRSA-16). J. Hosp. Infect. 29:87-106. - PubMed

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[1] Armstrong-Esther, C. A. 1976. Carriage patterns of Staphylococcus aureus in a healthy non-hospital population of adults and children. Ann. Hum. Biol. 3:221-227. - PubMed

[2] Armstrong-Esther, C. A. 1976. Carriage patterns of Staphylococcus aureus in a healthy non-hospital population of adults and children. Ann. Hum. Biol. 3:221-227. - PubMed

[3] Blot, S. I., K. H. Vandewoude, E. A. Hoste, and F. A. Colardyn. 2002. Outcome and attributable mortality in critically ill patients with bacteremia involving methicillin-susceptible and methicillin-resistant Staphylococcus aureus. Arch. Intern. Med. 162:2229-2235. - PubMed

[4] Blot, S. I., K. H. Vandewoude, E. A. Hoste, and F. A. Colardyn. 2002. Outcome and attributable mortality in critically ill patients with bacteremia involving methicillin-susceptible and methicillin-resistant Staphylococcus aureus. Arch. Intern. Med. 162:2229-2235. - PubMed

[5] Burke, R. E., M. S. Halpern, E. J. Baron, and K. Gutierrez. 2009. Pediatric and neonatal Staphylococcus aureus bacteremia: epidemiology, risk factors, and outcome. Infect. Control Hosp. Epidemiol. 30:636-644. - PubMed

[6] Burke, R. E., M. S. Halpern, E. J. Baron, and K. Gutierrez. 2009. Pediatric and neonatal Staphylococcus aureus bacteremia: epidemiology, risk factors, and outcome. Infect. Control Hosp. Epidemiol. 30:636-644. - PubMed

[7] Coello, R., J. Jimenez, M. Garcia, P. Arroyo, D. Minguez, C. Fernandez, F. Cruzet, and C. Gaspar. 1994. Prospective study of infection, colonization and carriage of methicillin-resistant Staphylococcus aureus in an outbreak affecting 990 patients. Eur. J. Clin. Microbiol. Infect. Dis. 13:74-81. - PubMed

[8] Coello, R., J. Jimenez, M. Garcia, P. Arroyo, D. Minguez, C. Fernandez, F. Cruzet, and C. Gaspar. 1994. Prospective study of infection, colonization and carriage of methicillin-resistant Staphylococcus aureus in an outbreak affecting 990 patients. Eur. J. Clin. Microbiol. Infect. Dis. 13:74-81. - PubMed

[9] Cox, R. A., C. Conquest, C. Mallaghan, and R. R. Marples. 1995. A major outbreak of methicillin-resistant Staphylococcus aureus caused by a new phage-type (EMRSA-16). J. Hosp. Infect. 29:87-106. - PubMed

[10] Cox, R. A., C. Conquest, C. Mallaghan, and R. R. Marples. 1995. A major outbreak of methicillin-resistant Staphylococcus aureus caused by a new phage-type (EMRSA-16). J. Hosp. Infect. 29:87-106. - PubMed

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Higher prevalence of pharyngeal than nasal Staphylococcus aureus carriage in pediatric intensive care units

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Higher prevalence of pharyngeal than nasal Staphylococcus aureus carriage in pediatric intensive care units

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