[Relapsing polychondritis and cartilage]

Rev Rhum Mal Osteoartic. 1991 Apr;58(4):283-6.
[Article in French]


Atrophic polychondritis (APC) results from elective lesions of the components of elastic cartilage. Clinical criteria have been established in terms of the incidence of auricular, nasal, ocular, tracheobronchial or cochlear involvement. However, recent clinical and pathological reviews have shown the frequency and severity of vascular lesions, aortic as well as peripheral. Several pathological mechanisms probably participate together in the destruction of elastic cartilage. A direct enzyme abnormality of glycoaminoglycanes and of elastic tissue are believed to be interlinked with an auto-immune process bringing type II anticollagen antibodies into play.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Cartilage / pathology*
  • Elastic Tissue / pathology
  • Humans
  • Polychondritis, Relapsing / etiology
  • Polychondritis, Relapsing / pathology*