Atypical childhood chronic inflammatory demyelinating polyneuropathy

Muscle Nerve. 2010 Aug;42(2):293-5. doi: 10.1002/mus.21703.


Chronic inflammatory demyelinating polyneuropathy (CIDP) is an uncommon cause of progressive weakness in childhood. The diagnosis is easy when the clinical history and findings are supported by unequivocal electrophysiologic and laboratory evidence of demyelination, but it can be challenging if the criteria for demyelination are not met. We report a case of atypical childhood CIDP to highlight the diagnostic difficulties and the importance of recognizing this treatable condition.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Disease Progression
  • Electrodiagnosis
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Male
  • Muscle Weakness / diagnosis*
  • Muscle Weakness / physiopathology
  • Muscle Weakness / therapy
  • Muscle, Skeletal / physiopathology
  • Neural Conduction / physiology
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / diagnosis*
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / physiopathology
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / therapy
  • Treatment Outcome


  • Immunoglobulins, Intravenous