Tropheryma whipplei in the skin of patients with classic Whipple's disease

J Infect. 2010 Sep;61(3):266-9. doi: 10.1016/j.jinf.2010.06.007. Epub 2010 Jun 19.


Positive Tropheryma whipplei PCR results in skin biopsies were frequent in patients with classic Whipple's disease without skin manifestations. The bacterium was alive, as a strain was successfully cultured. The skin may be a reservoir for T. whipplei and may be helpful in the non-invasive diagnosis of the disease.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Immunohistochemistry
  • Polymerase Chain Reaction
  • Skin / microbiology*
  • Tropheryma / genetics
  • Tropheryma / isolation & purification*
  • Whipple Disease / microbiology*