Context: Isolated pancreatic tuberculosis is a common mimicker of pancreatic malignancy and a common presentation is abdominal pain. However, segmental portal hypertension is very uncommon.
Case report: A case of isolated pancreatic tuberculosis mimicking focal pancreatitis and causing segmental portal hypertension is presented.
Conclusion: A histological or microbiological diagnosis of the presence of pancreatic masses is necessary to detect potentially treatable diseases, such as tuberculosis, in endemic countries like India.